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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T38359 | Dup-721 | Antibacterial | |
DuP-721 is a broad spectrum and orally active antibacterial agent. DuP-721 inhibits a variety of clinically susceptible and resistant bacteria, especially M. tuberculosis. | |||
T1426 | Pyrazinamide | Pyrazinoic acid amide,Pyrazinecarboxamide | Antibacterial , Antibiotic , Autophagy , Fatty Acid Synthase |
Pyrazinamide (Pyrazinecarboxamide), an antimycobacterial, is utilized therapeutically as an antitubercular agent, which is a synthetic pyrazinoic acid amide derivative. | |||
T8411 | C-215 | Others | |
C-215 is a novel inhibitor of mycobacterial membrane protein large 3 (MmpL3). | |||
T16339 | Norverapamil hydrochloride | (±)-Norverapamil hydrochloride,D591 hydrochloride | Calcium Channel , P-gp , Drug Metabolite |
Norverapamil hydrochloride (D591 hydrochloride) ((±)-Norverapamil hydrochloride) is an N-demethylated metabolite of Verapamil and it is an L-type calcium channel blocker and a P-glycoprotein (P-gp) function inhibitor. | |||
T25817 | Mitonafide | NSC-300288,NSC300288,NSC 300288 | Antibacterial |
Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent. | |||
T9830 | GSK2556286 | GSK286 | Antibacterial |
GSK2556286 (GSK286) is an orally active inhibitor of Mycobacterium tuberculosis (M. tuberculosis).GSK2556286 inhibits the growth of human macrophages with an IC50 value of 0.07 μM.GSK2556286 is effective against both mul... | |||
T5400 | Q203 | IAP6,Telacebec | Antibacterial , Antibiotic |
Q203 (Telacebec) is a novel potent anti-tuberculosis agent targeting cytochrome b subunit qcrB and inhibits M. tuberculosis H37Rv (MIC50: 2.7 nM). | |||
T5997 | TBAJ-587 | Antibacterial , Antibiotic | |
TBAJ-587 is a potent anti-tuberculosis agent. TBAJ-587 inhibits M.tb strain H37Rv growth with MIC90s of 0.006 and <0.02 µg/mL in MABA and LORA assay, respectively. BAJ-587 has more potent activity against M. tuberculosis... | |||
T7312 | AX20017 | Others , Antibacterial | |
AX20017 is a small-molecule protein kinase G (PknG) inhibitor(IC50 : 0.39 μM). It acts by blocking the proliferation of M. tuberculosis. | |||
T7342 | BM212 | Antibacterial | |
BM212 is an antimycobacterial compound.It inhibits the growth of laboratory and clinical isolate M. tuberculosis strains. | |||
T0020 | Sodium 4-aminosalicylate dihydrate | Sodium 4-Aminosalicylate,4-Amino-salicylic acid sodium salt | Free radical scavengers , NF-κB , Antibacterial , Antibiotic |
Sodium 4-aminosalicylate dihydrate (4-Amino-salicylic acid sodium salt) is the sodium salt form of aminosalicylic acid, an analog of para-aminobenzoic acid (PABA) with antitubercular activity. Sodium 4-aminosalicylate di... | |||
TQ0184 | Chebulinic acid | ATPase , Proton pump , DNA/RNA Synthesis , Antibacterial , TGF-beta/Smad | |
Chebulinic acid is a potent inhibitor of M. tuberculosis DNA gyrase. It also can inhibit SMAD-3 phosphorylation and H+ K+-ATPase activity. | |||
T4964 | Steviolbioside | CCRIS-6025 | Others |
Steviolbioside (CCRIS-6025) is a natural sweetener, it presents notable inhibition on human hepatocarcinoma cell Hep3B, human breast cancer cell MDA-MB-231 and human pancreatic cancer cell BxPC-3, thus, steviolbioside(CC... | |||
T27482 | GSK572A | Others | |
GSK572A is a novel and potent potent inhibitor of EchA6, which can be used to treat tuberculosis. | |||
T4531 | GSK2200150A | Antibacterial | |
GSK2200150A is an anti-tuberculosis (TB) agent identified by high-throughput screening (HTS) campaign. | |||
T60446 | LCS3 | Apoptosis , Glutathione reductase | |
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, in... | |||
T10563 | BM635 | Others | |
BM635 is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv). | |||
T10563L2 | BM635 mesylate (1493762-74-5 free base) | BM635 mesylate | Others |
BM635 mesylate is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv). | |||
T10563L | BM635 hydrochloride (1493762-74-5 free base) | BM635 hydrochloride | Others |
BM635 hydrochloride is an MmpL3 inhibitor with outstanding anti-mycobacterial activity (MIC50: 0.12 μM against M. tuberculosis H37Rv). | |||
T39693 | Polyketide synthase 13-IN-3 | ||
Polyketide synthase 13-IN-3 (compound 41) is a potent inhibitor of polyketide synthase 13, demonstrating a minimum inhibitory concentration (MIC) range of 0.0625-0.125 μg/mL against the M. tuberculosis strain H37Rv. |